A Multicentre Randomized Trial Of Ablation Based Rhythm Control Versus Rate Control

By hairstyler On Nov 12, 2025

AHA 2022: A Randomized Ablation-based Atrial Fibrillation Rhythm ...

AHA 2022: A Randomized Ablation-based Atrial Fibrillation Rhythm ... Ablation based rhythm control was compared with rate control to evaluate if clinical outcomes in patients with hf and af could be improved. methods: this was a multicenter, open label trial with blinded outcome evaluation using a central adjudication committee. Patients are randomized to either rate control or catheter ablation based af rhythm control in a 1:1 ratio. patients in the rate control group receive optimal hf therapy and rate control measures to achieve a resting hazard ratio (hr) < 80 bpm and 6 minute walk hr < 110 bpm.

Table 1 From Randomized Ablation-Based Rhythm-Control Versus Rate ...

Table 1 From Randomized Ablation-Based Rhythm-Control Versus Rate ... Access this presentation on esc 365 from esc congress 2024 on catheter ablation of arrhythmias by doctor a. tang (canada,ca) on esc 365. We included studies that compared the efficacy of rhythm control (ie, antiarrhythmic drugs classes ia, ic, or iii, af catheter ablation, and electrical cardioversion) and rate control (ie, beta blocker, digitalis, or calcium antagonist) strategies among patients with nonvalvular af. Ablation based rhythm control was compared with rate control to evaluate if clinical outcomes in patients with hf and af could be improved. this was a multicenter, open label trial with blinded outcome evaluation using a central adjudication committee. Effect size is an estimate of the difference between groups taking into account of time and competing risk of death.

Randomized Controlled Trial For Pulsed Field Ablation Versus Standard ...

Randomized Controlled Trial For Pulsed Field Ablation Versus Standard ... Ablation based rhythm control was compared with rate control to evaluate if clinical outcomes in patients with hf and af could be improved. this was a multicenter, open label trial with blinded outcome evaluation using a central adjudication committee. Effect size is an estimate of the difference between groups taking into account of time and competing risk of death. This first randomized trial of ablation versus rate control to focus on objective exercise performance in af and hf shows significant benefit from ablation, a strategy that also improves symptoms and neurohormonal status. This chapter reviews the historical, pivotal rate versus rhythm control trials that failed to show any overall survival benefit of rhythm over rate control, as well as the trials’ now recognized limitations with respect to modern therapy. We therefore sought to perform a comprehensive updated systematic review and meta analysis to synthesize the evidence from contemporary randomized controlled trials (rcts) pertaining to rhythm versus rate control of af in hf, focusing especially on outcomes by clinical characteristics. The landmark affirm (atrial fibrillation follow up investigation of rhythm management) trial 1 was the first, and one of the largest, clinical studies to compare the use of rate control vs rhythm control for atrial fibrillation (af) patients.

An Overview Of Published Randomized Trials Of Rhythm Control Versus ...

An Overview Of Published Randomized Trials Of Rhythm Control Versus ... This first randomized trial of ablation versus rate control to focus on objective exercise performance in af and hf shows significant benefit from ablation, a strategy that also improves symptoms and neurohormonal status. This chapter reviews the historical, pivotal rate versus rhythm control trials that failed to show any overall survival benefit of rhythm over rate control, as well as the trials’ now recognized limitations with respect to modern therapy. We therefore sought to perform a comprehensive updated systematic review and meta analysis to synthesize the evidence from contemporary randomized controlled trials (rcts) pertaining to rhythm versus rate control of af in hf, focusing especially on outcomes by clinical characteristics. The landmark affirm (atrial fibrillation follow up investigation of rhythm management) trial 1 was the first, and one of the largest, clinical studies to compare the use of rate control vs rhythm control for atrial fibrillation (af) patients.