Autoimmune Bullous Diseases Intechopen

Autoimmune Bullous Diseases Pdf Immune System B Cell Autoimmune bullous diseases are a group of rare skin diseases characterized by intraepidermal and subepidermal bullae formations due to autoantibodies directed against the structural proteins of the epidermis or the dermal epidermal junction. Autoimmune bullous diseases (abd) are a heterogeneous group of rare but fatal or debilitating skin diseases characterized by varying degrees of mucosal and cutaneous blister formation due to autoantibodies directed against the structural proteins of epidermis or the dermal epidermal junction [2, 3]. abd are classified according to the location.

Autoimmune Bullous Diseases Intechopen Autoimmune bullous diseases belong to disorders that have low incidence but a high morbidity and mortality. rupturing of blisters leads to painful erosions that cause significant loss of body fluid, electrolytes and proteins, especially in cases with extensive body surface involvement. In this chapter, practical histopathology and direct immu nofluorescence findings of autoimmune bullous disease are discussed and supported by illustrative microphotographs taken from cases within our institution. 1. introduction. autoimmune bullous diseases can be debilitating or even fatal. Autoimmune bullous diseases warrant the use of high dose of systemic corticosteroids and immunosuppressive drugs that may be associated with various adverse and other side effects. moreover, considerable risk for serious systemic complications should be predicted. Materials and methods: this review explores the evolving landscape of therapeutic options for immunobullous diseases, with a particular focus on pemphigus, bullous pemphigoid (bp), and mucous membrane pemphigoid, by searching pubmed, clinicaltrials.gov, and cochrane databases for published literature from 2014 to 2023.

Wound Care In Immunobullous Disease Intechopen Autoimmune bullous diseases warrant the use of high dose of systemic corticosteroids and immunosuppressive drugs that may be associated with various adverse and other side effects. moreover, considerable risk for serious systemic complications should be predicted. Materials and methods: this review explores the evolving landscape of therapeutic options for immunobullous diseases, with a particular focus on pemphigus, bullous pemphigoid (bp), and mucous membrane pemphigoid, by searching pubmed, clinicaltrials.gov, and cochrane databases for published literature from 2014 to 2023. Pemphigus is a group of autoimmune blistering disorders associated with autoantibod ies against the keratinocyte cell surface. pemphigus has three major variants: pemphigus vulgaris (pv), pemphigus foliaceus (pf), and paraneoplastic pemphigus (pnp) which all have further subtypes. Intraepidermal and subepidermal bullae formation. a utoantibodies to major players of. targeted by autoantibodies. a utoimmune bullous diseases can be divided into four basic. of target. Autoimmune bullous diseases can be debilitating or even fatal. therefore, disease control is crucial, and this cannot be achieved without a definitive diagnosis. one of the most important diagnostic tools is light microscopic findings with the additional support of immunofluorescence results. Autoimmune bullous diseases are a heterogeneous group of skin diseases clinically characterized by erosions and or blisters on the skin and mucous membranes. the autoantibodies targeting epidermal or subepidermal adhesion proteins lead to a loss in skin integrity, which manifests clinically as the formation of blisters.