Raskolnikov By Saskle On Deviantart The human il 3 gene encodes a protein 152 amino acids long, and the naturally occurring il 3 is glycosylated. the human il 3 gene is located on chromosome 5, only 9 kilobases from the gm csf gene, and its function is quite similar to gm csf. Depending on the type of disease, the course of inflammation, the cell or the tissue involved, il 3 promotes either pathologic inflammation or its resolution. here, we describe the cell specific functions of il 3 and summarize its role in diseases.
Explore The Best Raskolnikov Art Deviantart Interleukin 3 (il 3) belongs to a family of proteins called cytokines, which cells use to send messages to one another. produced mainly by activated immune cells called t cells, this protein’s primary job is to act as a growth foreman for the body’s blood cell factory, the bone marrow. Interleukin 3 il 3 binds to a receptor composed of a unique il 3rα subunit and the common βc subunit. il 3 synergizes with other cytokines to stimulate the growth of immature progenitor cells of all lineages, and is therefore a multi lineage colony stimulating factor (csf). Another area of very significant interest is the role of il 3 in cancer biology. the available evidence suggests that il 3 may directly or indirectly promote tumorigenesis and progression, acting through its effects on the tumor microenvironment. Interleukin (il) 3 has long been known for its hematopoietic properties. however, recent evidence has expanded our understanding of il 3 function by identifying il 3 as a critical orchestrator of inflammation in a wide array of diseases.
Raskolnikov By Spaska On Deviantart Another area of very significant interest is the role of il 3 in cancer biology. the available evidence suggests that il 3 may directly or indirectly promote tumorigenesis and progression, acting through its effects on the tumor microenvironment. Interleukin (il) 3 has long been known for its hematopoietic properties. however, recent evidence has expanded our understanding of il 3 function by identifying il 3 as a critical orchestrator of inflammation in a wide array of diseases. By using a cdna clone, ihle et al. (1987) mapped the il3 gene to mouse chromosome 11 in a series of hamster x mouse somatic cell hybrids. to confirm the chromosomal assignment, they sought evidence for linkage between il3 and other genes on chromosome 11. The cytokine interleukin 3 (il 3) is mainly produced by activated t cells. il 3 is also called multi lineage colony stimulating factor since it induces the growth and differentiation of many cells. Interleukin 3 (il 3) is a signaling molecule, a cytokine, that facilitates cell communication throughout the body. cytokines help regulate the body’s responses to various stimuli, including inflammation and infection. Given that astrocytes generate il 3 at the steady state, it is reasonable to speculate that il 3 might play a role in neurodevelopment, cognitive processing, or behavior.
Raskolnikov By Vanilca On Deviantart By using a cdna clone, ihle et al. (1987) mapped the il3 gene to mouse chromosome 11 in a series of hamster x mouse somatic cell hybrids. to confirm the chromosomal assignment, they sought evidence for linkage between il3 and other genes on chromosome 11. The cytokine interleukin 3 (il 3) is mainly produced by activated t cells. il 3 is also called multi lineage colony stimulating factor since it induces the growth and differentiation of many cells. Interleukin 3 (il 3) is a signaling molecule, a cytokine, that facilitates cell communication throughout the body. cytokines help regulate the body’s responses to various stimuli, including inflammation and infection. Given that astrocytes generate il 3 at the steady state, it is reasonable to speculate that il 3 might play a role in neurodevelopment, cognitive processing, or behavior.
Explore The Best Raskolnikov Art Deviantart Interleukin 3 (il 3) is a signaling molecule, a cytokine, that facilitates cell communication throughout the body. cytokines help regulate the body’s responses to various stimuli, including inflammation and infection. Given that astrocytes generate il 3 at the steady state, it is reasonable to speculate that il 3 might play a role in neurodevelopment, cognitive processing, or behavior.
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